New article on comparison of methods in wine metabolomics

Qualitative factor-based comparison of NMR, targeted and untargeted GC-MS and LC-MS on the metabolomic profiles of Rioja and Priorat red wines. 

Dimitrios Kioroglou, Albert Mas, M. Carmen Portillo

Foods 9, 1381 : https://www.mdpi.com/2304-8158/9/10/1381

    Wine origin and ageing are two factors related to wine quality which in turn is associated to wine metabolome. Currently, new metabolomic techniques and proper statistics procedures allow accurate profiling of wine metabolome. 

    In the current study, we implement NMR, targeted and untargeted GC-MS and LC-MS metabolomic analytical techniques so as to gain insights into the volatile and nonvolatile wine metabolome composition of red wines from two cellars located in the only two Spanish Qualified Appellations of Origin:DOQ Priorat and DOCa Rioja regions. 

    The results suggest that a combination of different metabolomic techniques is necessary for a complete overview of the metabolome changes and ease the selection of the correct methodology depending on the specific factor investigated.